Where does melanoma spread to first?
Normally, the first place a melanoma tumor metastasizes to is the lymph nodes, by literally draining melanoma cells into the lymphatic fluid, which carries the melanoma cells through the lymphatic channels to the nearest lymph node basin..
Does melanoma always metastasize?
While melanomas rarely recur locally at the site of excision, they often recur as metastases at distant sites . Even in Stage IA melanoma patients, who have a 20-year survival rate of at least 90%, recurrences of disease still occur, often a decade or more after the removal of the primary tumor .
What are the odds of melanoma spreading?
Patients with melanoma are also at risk of recurrence of their original cancer. Second primary melanomas develop at a rate of approximately 0.5 percent per year for the first five years and at a lower rate thereafter.
Can you have stage 4 melanoma and not know it?
Sometimes the symptoms for stage 4 melanoma may not appear for many years after the original tumor was removed. Talk to your doctor if you’re feeling new pains and aches or symptoms. They’ll be able to help diagnose the cause and recommend treatment options.
Do you feel unwell with melanoma?
General symptoms hard or swollen lymph nodes. hard lump on your skin. unexplained pain. feeling very tired or unwell.
How do you know if melanoma has spread?
If your melanoma has spread to other areas, you may have:Hardened lumps under your skin.Swollen or painful lymph nodes.Trouble breathing, or a cough that doesn’t go away.Swelling of your liver (under your lower right ribs) or loss of appetite.Bone pain or, less often, broken bones.More items…•