Question: What Are The Contraindications Of Atropine?

Why is atropine contraindicated in myasthenia gravis?

Atropine should be avoided in patients with myasthenia gravis, because the anticholinergic competes with the small amount of acetylcholine that has potential to act in the bodies of these patients..

What is atropine used for in emergency situations?

Atropine is used to help reduce saliva, mucus, or other secretions in your airway during a surgery. Atropine is also used to treat spasms in the stomach, intestines, bladder, or other organs. Atropine is sometimes used as an antidote to treat certain types of poisoning.

Does atropine affect blood pressure?

However, when given by itself, atropine does not exert a striking or uniform effect on blood vessels or blood pressure. Systemic doses slightly raise systolic and lower diastolic pressures and can produce significant postural hypotension.

Is atropine a poison?

Because of the hallucinogenic properties, some have used the drug recreationally, though this is potentially dangerous and often unpleasant. In overdoses, atropine is poisonous.

Why is atropine used in myasthenia gravis?

To minimize these side effects, your physician might lower the dose of cholinesterase inhibitors or prescribe atropine, which blocks the ACh receptors on nerve cells. Patients with limb and bulbar symptoms typically respond better to pyridostigmine than those with ptosis and diplopia.

Why is atropine given for bradycardia?

Atropine works by poisoning the vagus nerve, thereby removing parasympathetic inputs to the heart. This works beautifully for vagally-mediated bradycardia (e.g. vagal reflexes, cholinergic drugs). However, it fails for bradycardias caused by other mechanisms (e.g. heart block beyond the AV node).

When should you not take atropine?

Atropine should be avoided with bradycardia caused by hypothermia and, in most cases, it will not be effective for Mobitz type II/Second-degree block type 2 or complete heart block.

How is atropine poisoning treated?

Specific treatmentGive physostigmine salicylate, 0.5–1 mg intravenously slowly over 5 minutes, with ECG monitoring.Repeat as needed to total dose of no more than 2 mg.

Why Atropine is given in OP poisoning?

Atropine is given to poisoned patients to block muscarinic overstimulation. However, neuromuscular blocking agents (nicotinic acetylcholine receptor antagonists) are not currently used to prevent nicotinic overstimulation 57.

Is atropine a narcotic?

What is diphenoxylate and atropine, and how does it work (mechanism of action)? Lomotil is a combination of two drugs, diphenoxylate and atropine. It is used to treat acute diarrhea (diarrhea of limited duration). Diphenoxylate is a man-made narcotic chemically related to meperidine (Demerol).

Why is atropine contraindicated in glaucoma?

Antimuscarinics such as atropine are contraindicated in angle-closure glaucoma because of the increased likelihood of producing complete obstruction of the outflow of aqueous humor, resulting in an acute increase in intraocular pressure (IOP) in response to relaxation of the ciliary muscle.

Why is atropine given?

Atropine is used to help reduce saliva, mucus, or other secretions in your airway during a surgery. Atropine is also used to treat spasms in the stomach, intestines, bladder, or other organs. Atropine is sometimes used as an antidote to treat certain types of poisoning.

How long does the effects of atropine last?

How long do the effects of the atropine last? The blurred vision, caused by the atropine, will last for approximately seven days after the last instillation. The dilated pupil may remain for as long as 14 days.

How fast should atropine be given?

Atropine should be administered by rapid IV push and may be repeated every 3-5 minutes, to a maximum dose of 3 mg.

What happens if you give too much atropine?

Excess doses of atropine sulfate may cause side effects such as palpitations, dilated pupils, difficulty swallowing, hot dry skin, thirst, dizziness, restlessness, tremor, fatigue, and problems with coordination.

Why is atropine contraindicated in asthma?

Conditions at which inhibition of postganglionic cholinergic nerves are undesirable, such as glaucoma and tachycardia. Also contraindicated in asthma, because the parenteral dose which might relieve asthma would have an excessive drying effect upon mucous plugs in the bronchi.

What does atropine do to the body?

Atropine produces many effects in the body, including reducing stomach or intestinal spasms, reducing the production of saliva, mucus, and other bodily secretions, and maintaining proper heart rhythm.

Does atropine increase heart rate?

Atropine increases the heart rate and improves the atrioventricular conduction by blocking the parasympathetic influences on the heart.

What drug class is atropine?

Atropine is commonly classified as an anticholinergic or antiparasympathetic (parasympatholytic) drug. More precisely, however, it is termed an antimuscarinic agent since it antagonizes the muscarine-like actions of acetylcholine and other choline esters.

Why is atropine poisonous?

Ingestion of as little as a few drops of atropine in eye drop formulation can cause anticholinergic, or more specifically antimuscarinic, toxicity. The antimuscarinic toxidrome results from blockade of the neurotransmitter acetylcholine at central and peripheral muscarinic receptors.

Can atropine cause heart attack?

In patients with a recent myocardial infarction and/or severe coronary artery disease, there is a possibility that atropine-induced tachycardia may cause ischemia, extend or initiate myocardial infarcts, and stimulate ventricular ectopy and fibrillation.